sothat和so...that的区别是用法不同、可替换短语不同、释义不同。so that的意思是以致、为了、以便于；so…that…的意思是如此……以致。o that 引导目的状语从句，常放于句中；so…that…中so是副词，常常用来修饰形容词和副词。

例句：（1）My sister made a model plane so that she could help with her friend studying the science last night.昨天晚上我妹妹制作了一个飞机模型以便她能帮助她的朋友学习科学。（2）She is so beautiful that all boys want to make friends with her. 她是如此的美丽以至于所有的男孩们都想和她做朋友。