沮丧用英语可以表达为 "depression" 或 "despondency." 来源于拉丁语，depression 来自拉丁语 "depressio"，意思是 "压抑"，despondency 来自拉丁语 "despondere"，意思是 "绝望"。

例句：

His depression was so severe that he could barely get out of bed in the morning. (他的抑郁症非常严重，以至于他几乎早上都没有办法起床。)

She felt a sense of despondency as she realized she had failed her exams. (当她意识到自己考试不及格时，她感到绝望。)