In English, we would say "to play the flute" when referring to the act of blowing into and producing music with a flute. The word "flute" comes from the Old French word "flaute" and ultimately derives from the Latin word "flatus," which means "blow" or "breath." Here are some example sentences:

I love to hear the sound of the flute. (我喜欢听笛子的声音。)

She has been playing the flute for many years. (她已经吹笛子很多年了。)

He is a skilled flute player. (他是一名熟练的笛子演奏者。)